Title : Two distinct mechanisms target the autophagy-related E3 complex to the pre-autophagosomal structure.

Pub. Date : 2019 Feb 27

PMID : 30810528






2 Functional Relationships(s)
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1 Previous studies in yeast revealed that the autophagy-related E3 complex Atg12-Atg5-Atg16 is recruited to the PAS via Atg16 interaction with Atg21, which binds phosphatidylinositol 3-phosphate (PI3P) produced at the PAS, to stimulate conjugation of the ubiquitin-like protein Atg8 to phosphatidylethanolamine. Aminosalicylic Acid Atg21p Saccharomyces cerevisiae S288C
2 Previous studies in yeast revealed that the autophagy-related E3 complex Atg12-Atg5-Atg16 is recruited to the PAS via Atg16 interaction with Atg21, which binds phosphatidylinositol 3-phosphate (PI3P) produced at the PAS, to stimulate conjugation of the ubiquitin-like protein Atg8 to phosphatidylethanolamine. Aminosalicylic Acid Atg21p Saccharomyces cerevisiae S288C