Title : Valproate and myoclonus.

Pub. Date : 1986

PMID : 3080855






1 Functional Relationships(s)
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1 Elevation in brain GABA level occurs in parallel with the anticonvulsant activity observed following valproate administration, and high levels of valproate inhibit the GABA-metabolizing enzymes GABA-T and SSADH and cause a reduction in the rate of GABA turnover. Valproic Acid 4-aminobutyrate aminotransferase Homo sapiens