Title : Design, synthesis and evaluation of d-amino acid-containing peptidomimetics targeting the polo-box domain of polo-like kinase 1.

Pub. Date : 2019 Apr

PMID : 30807896






4 Functional Relationships(s)
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1 A series of d-amino acid-containing peptidomimetics were designed, synthesized as novel polo-like kinase 1 (Plk1) polo-box domain (PBD) inhibitors based on the reported peptide Plk1 PBD inhibitor. d-amino acid polo like kinase 1 Homo sapiens
2 A series of d-amino acid-containing peptidomimetics were designed, synthesized as novel polo-like kinase 1 (Plk1) polo-box domain (PBD) inhibitors based on the reported peptide Plk1 PBD inhibitor. d-amino acid polo like kinase 1 Homo sapiens
3 A series of d-amino acid-containing peptidomimetics were designed, synthesized as novel polo-like kinase 1 (Plk1) polo-box domain (PBD) inhibitors based on the reported peptide Plk1 PBD inhibitor. d-amino acid polo like kinase 1 Homo sapiens
4 These novel d-amino acid modified selective Plk1 PBD inhibitors may provide new lead compounds for further optimization. d-amino acid polo like kinase 1 Homo sapiens