Title : PI3K/Akt Pathway and miR-21 are Involved in N-Ethyl-N-Nitrosourea-Induced F1 Mouse Lung Tumorigenesis: Effect of Inositol Hexaphosphate.

Pub. Date : 2019

PMID : 30806292






2 Functional Relationships(s)
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1 IP6-fed F1 mice showed reduced tumorigenesis along with reduced expression of the PI3K/Akt pathway miR-21 and downstream targets. Phytic Acid thymoma viral proto-oncogene 1 Mus musculus
2 The PI3K/Akt pathway and miR-21 are involved in transplacental lung tumorigenesis, whereas IP6 seemed to affect lung tumorigenesis by suppressing the expression of the PI3K/Akt pathway in F1 mice. Phytic Acid thymoma viral proto-oncogene 1 Mus musculus