Title : Garcinol Sensitizes NSCLC Cells to Standard Therapies by Regulating EMT-Modulating miRNAs.

Pub. Date : 2019 Feb 13

PMID : 30781783






2 Functional Relationships(s)
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1 We used A549 cells that were exposed to transforming growth factor beta 1 (TGF-beta1), resulting in A549M cells with mesenchymal and drug resistant phenotype, and report that garcinol sensitized resistant cells with mesenchymal phenotype to erlotinib as well as cisplatin with significant decrease in their IC50 values. garcinol transforming growth factor beta 1 Homo sapiens
2 We used A549 cells that were exposed to transforming growth factor beta 1 (TGF-beta1), resulting in A549M cells with mesenchymal and drug resistant phenotype, and report that garcinol sensitized resistant cells with mesenchymal phenotype to erlotinib as well as cisplatin with significant decrease in their IC50 values. garcinol transforming growth factor beta 1 Homo sapiens