Title : Nasal delivery of Fasudil-modified immune cells exhibits therapeutic potential in experimental autoimmune encephalomyelitis.

Pub. Date : 2019 Jun

PMID : 30779332






1 Functional Relationships(s)
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1 Fasudil-modified MNCs inhibited the activation of inflammatory signaling p-NF-kB/P38, accompanied by the decrease of COX-2 and the increase of Arg-1 in spinal cord, as well as the reduction of IL-17, TNF-alpha, IL-6 and the elevation of IL-10 in cultured supernatant of splenocytes. fasudil mitogen-activated protein kinase 14 Mus musculus