Title : NAD+ metabolism governs the proinflammatory senescence-associated secretome.

Pub. Date : 2019 Mar

PMID : 30778219






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 HMGA proteins and NAMPT promote the proinflammatory SASP through NAD+-mediated suppression of AMPK kinase, which suppresses the p53-mediated inhibition of p38 MAPK to enhance NF-kappaB activity. NAD tumor protein p53 Homo sapiens