Title : ERK Inhibitor Enhances Everolimus Efficacy through the Attenuation of dNTP Pools in Renal Cell Carcinoma.

Pub. Date : 2019 Mar 1

PMID : 30771617






1 Functional Relationships(s)
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1 The combination treatment markedly attenuated the deoxyribonucleoside triphosphate (dNTP) pools by downregulating the mRNA expression of RRM1 and RRM2 through E2F1. Parathion ribonucleotide reductase catalytic subunit M1 Homo sapiens