Pub. Date : 2019 Aug
PMID : 30770549
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Curcumin prevents high glucose damage in retinal pigment epithelial cells through ERK1/2-mediated activation of the Nrf2/HO-1 pathway. | Curcumin | heme oxygenase 1 | Homo sapiens |
| 2 | Further, curcumin was able to induce HO-1 expression via Nrf2 activation and counteracts the damage elicited by HG. | Curcumin | heme oxygenase 1 | Homo sapiens |
| 3 | The present study demonstrated that curcumin provides protection against HG-induced damage in RPE cells through the activation of Nrf2/HO-1 signaling that involves the ERK pathway, suggesting that curcumin may have therapeutic value in the treatment of diabetic retinopathy. | Curcumin | heme oxygenase 1 | Homo sapiens |
| 4 | The present study demonstrated that curcumin provides protection against HG-induced damage in RPE cells through the activation of Nrf2/HO-1 signaling that involves the ERK pathway, suggesting that curcumin may have therapeutic value in the treatment of diabetic retinopathy. | Curcumin | heme oxygenase 1 | Homo sapiens |