Title : Brivanib in combination with Notch3 silencing shows potent activity in tumour models.

Pub. Date : 2019 Mar

PMID : 30765875






2 Functional Relationships(s)
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1 RESULTS: Using a proteomic approach, we have shown that Notch3 is strongly involved in brivanib resistance through a p53-dependent regulation of enzymes of the tricarboxylic acid (TCA), both in vitro and in vivo. Tricarboxylic Acids tumor protein p53 Homo sapiens
2 RESULTS: Using a proteomic approach, we have shown that Notch3 is strongly involved in brivanib resistance through a p53-dependent regulation of enzymes of the tricarboxylic acid (TCA), both in vitro and in vivo. Tricarboxylic Acids tumor protein p53 Homo sapiens