Pub. Date : 2019 Feb 14
PMID : 30765766
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Indispensable role of beta-arrestin2 in the protection of remifentanil preconditioning against hepatic ischemic reperfusion injury. | Remifentanil | arrestin, beta 2 | Mus musculus |
| 2 | Remifentanil increased beta-arrestin2 expression both in vivo and in vitro, while after silencing beta-arrestin2 RNA, the effect of remifentanil in reducing cell death and apoptosis, as well as decreasing phosphorylation of ERK and JNK were abolished in RAW264.7 cells. | Remifentanil | arrestin, beta 2 | Mus musculus |
| 3 | Remifentanil increased beta-arrestin2 expression both in vivo and in vitro, while after silencing beta-arrestin2 RNA, the effect of remifentanil in reducing cell death and apoptosis, as well as decreasing phosphorylation of ERK and JNK were abolished in RAW264.7 cells. | Remifentanil | arrestin, beta 2 | Mus musculus |
| 4 | These data suggested that remifentanil could ameliorate mice HIRI through upregulating beta-arrestin2 expression, which may function as a key molecule in bridging opioid receptor and TLR4 pathway. | Remifentanil | arrestin, beta 2 | Mus musculus |