Pub. Date : 2019 Feb 14
PMID : 30765766
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Using the rodent models of hepatic ischemia reperfusion injury both in wild type and TLR4 knockout (TLR4 KO) mice, we found that remifentanil preconditioning could inhibit the expression of TLR4 and reduce the inflammatory response induced by HIRI in wild type but not in TLR4 KO mice. | Remifentanil | toll-like receptor 4 | Mus musculus |
2 | Using the rodent models of hepatic ischemia reperfusion injury both in wild type and TLR4 knockout (TLR4 KO) mice, we found that remifentanil preconditioning could inhibit the expression of TLR4 and reduce the inflammatory response induced by HIRI in wild type but not in TLR4 KO mice. | Remifentanil | toll-like receptor 4 | Mus musculus |
3 | Using the rodent models of hepatic ischemia reperfusion injury both in wild type and TLR4 knockout (TLR4 KO) mice, we found that remifentanil preconditioning could inhibit the expression of TLR4 and reduce the inflammatory response induced by HIRI in wild type but not in TLR4 KO mice. | Remifentanil | toll-like receptor 4 | Mus musculus |
4 | Using the rodent models of hepatic ischemia reperfusion injury both in wild type and TLR4 knockout (TLR4 KO) mice, we found that remifentanil preconditioning could inhibit the expression of TLR4 and reduce the inflammatory response induced by HIRI in wild type but not in TLR4 KO mice. | Remifentanil | toll-like receptor 4 | Mus musculus |
5 | These data suggested that remifentanil could ameliorate mice HIRI through upregulating beta-arrestin2 expression, which may function as a key molecule in bridging opioid receptor and TLR4 pathway. | Remifentanil | toll-like receptor 4 | Mus musculus |