Pub. Date : 2019 May
PMID : 30763886
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Our best hit, 4d (COX-1 IC50 of 28 microM, COX-2 IC50 of 23 microM), appears to adopt similar binding modes to the standard COX-2 inhibitor, celecoxib, proposing room for possible selectivity. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | Four compounds 3a (COX-2 IC50 of 42 microM), 3d, 4d and 4f were notable for their anti-inflammatory activity that was comparable to that of the clinically available COX-2 inhibitor celecoxib. | Celecoxib | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |