Pub. Date : 2019 Jun
PMID : 30761522
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | KEY RESULTS: The EP2 receptor is a key Galphas -coupled receptor that mediates COX-2/PGE2 -initiated cAMP signalling pathways in human malignant glioma cells. | Dinoprostone | prostaglandin E receptor 2 | Homo sapiens |
| 2 | CONCLUSION AND IMPLICATIONS: Taken together, our results suggest that PGE2 signalling via the EP2 receptor increases the malignant potential of human glioma cells and might represent a novel therapeutic target for GBM. | Dinoprostone | prostaglandin E receptor 2 | Homo sapiens |