Title : BRD4 Inhibition Enhances Azacitidine Efficacy in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

Pub. Date : 2019

PMID : 30761268






2 Functional Relationships(s)
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1 BRD4 Inhibition Enhances Azacitidine Efficacy in Acute Myeloid Leukemia and Myelodysplastic Syndromes. Azacitidine bromodomain containing 4 Homo sapiens
2 Furthermore, the inhibition of BRD4 in vitro with JQ1 or shRNA induced leukemia cell apoptosis, especially when combined to azacitidine, and triggered the activation of the DNA damage response pathway. Azacitidine bromodomain containing 4 Homo sapiens