Pub. Date : 2019 Feb 12
PMID : 30755224
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PRIMA-1MET-induced neuroblastoma cell death is modulated by p53 and mycn through glutathione level. | Glutathione | tumor protein p53 | Homo sapiens |
| 2 | Variations of MYCN and p53 modulated intracellular levels of GSH and resulted in increased/decreased sensitivity of PRIMA-1MET. | Glutathione | tumor protein p53 | Homo sapiens |
| 3 | Although p53 is involved in PRIMA-1MET-mediated cell death, our results suggest that direct interaction with p53 has a limited role in neuroblastoma but rather acts through modulation of GSH levels. | Glutathione | tumor protein p53 | Homo sapiens |