Pub. Date : 2019 May 1
PMID : 30753572
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ceftazidime/avibactam resistance associated with L169P mutation in the omega loop of KPC-2. | avibactam | carbapenem-hydrolyzing beta-lactamase KPC-2 | Klebsiella pneumoniae |
| 2 | OBJECTIVES: Ceftazidime/avibactam resistance due to mutation in the omega loop of KPC-2 has been documented in vitro and in vivo. | avibactam | carbapenem-hydrolyzing beta-lactamase KPC-2 | Klebsiella pneumoniae |
| 3 | This study evaluated the mechanism of ceftazidime/avibactam resistance in a KPC-2-expressing Klebsiella pneumoniae isolated from a patient following ceftazidime/avibactam combination therapy with gentamicin for the treatment of ventilator-associated pneumonia. | avibactam | carbapenem-hydrolyzing beta-lactamase KPC-2 | Klebsiella pneumoniae |
| 4 | This study evaluated the mechanism of ceftazidime/avibactam resistance in a KPC-2-expressing Klebsiella pneumoniae isolated from a patient following ceftazidime/avibactam combination therapy with gentamicin for the treatment of ventilator-associated pneumonia. | avibactam | carbapenem-hydrolyzing beta-lactamase KPC-2 | Klebsiella pneumoniae |