Title : Carbonic anhydrase-IX inhibition enhances the efficacy of hexokinase II inhibitor for hepatocellular carcinoma in a murine model.

Pub. Date : 2019 Apr

PMID : 30746618






1 Functional Relationships(s)
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1 3-bromopyruvate (3-BP), a hexokinase II inhibitor, and acetazolamide, a carbonic anhydrase inhibitor, were used to target hexokinase II and CA-IX in vitro and in vivo, respectively. Acetazolamide carbonic anhydrase 9 Homo sapiens