Pub. Date : 2019 Jun
PMID : 30742493
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Pendrin Mediates Bicarbonate Secretion and Enhances Cystic Fibrosis Transmembrane Conductance Regulator Function in Airway Surface Epithelia. | Bicarbonates | solute carrier family 26 member 4 | Homo sapiens |
2 | The anion exchanger pendrin (SLC26A4) also mediates HCO3- efflux and is upregulated by proinflammatory cytokines. | Bicarbonates | solute carrier family 26 member 4 | Homo sapiens |
3 | The anion exchanger pendrin (SLC26A4) also mediates HCO3- efflux and is upregulated by proinflammatory cytokines. | Bicarbonates | solute carrier family 26 member 4 | Homo sapiens |
4 | We conclude that pendrin mediates most HCO3- secretion across airway surface epithelium during inflammation and enhances electrogenic Cl- secretion via CFTR, as described for other SLC26A transporters. | Bicarbonates | solute carrier family 26 member 4 | Homo sapiens |