Pub. Date : 2019 Sep
PMID : 30738802
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Lumacaftor-rescued F508del-CFTR has a modified bicarbonate permeability. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 2 | We studied the permeability properties of the CFTR mutant F508del treated with the corrector lumacaftor, showing that the rescued protein has selectivity properties different than the wild type CFTR, showing an augmented bicarbonate permeability. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 3 | We studied the permeability properties of the CFTR mutant F508del treated with the corrector lumacaftor, showing that the rescued protein has selectivity properties different than the wild type CFTR, showing an augmented bicarbonate permeability. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |
| 4 | Our findings rather support the idea that a combination of correctors would be required to address the CFTR-dependent bicarbonate permeability. | Bicarbonates | CF transmembrane conductance regulator | Homo sapiens |