Pub. Date : 2019 Aug
PMID : 30737481
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Exposure to neonatal alcohol resulted in acute increases in activation and inflammatory gene expression in hypothalamic microglia including tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6). | Alcohols | interleukin 6 | Homo sapiens |
| 2 | Exposure to neonatal alcohol resulted in acute increases in activation and inflammatory gene expression in hypothalamic microglia including tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6). | Alcohols | interleukin 6 | Homo sapiens |
| 3 | Investigation of possible epigenetic programming mechanisms by alcohol revealed neonatal alcohol decreased several repressive regulators of transcription in hypothalamic microglia, while concomitantly increasing histone H3 acetyl lysine 9 (H3K9ac) enrichment at TNF-alpha and IL-6 promoter regions. | Alcohols | interleukin 6 | Homo sapiens |