Title : ABCB4/MDR3 in health and disease - at the crossroads of biochemistry and medicine.

Pub. Date : 2019 Sep 25

PMID : 30730833






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Among these transporters, ABCB4 is essential for the translocation of phosphatidylcholine (PC) lipids from the inner to the outer leaflet of the canalicular membrane of hepatocytes. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens
2 Among these transporters, ABCB4 is essential for the translocation of phosphatidylcholine (PC) lipids from the inner to the outer leaflet of the canalicular membrane of hepatocytes. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens
3 ABCB4 deficiency can result in altered PC to bile salt ratios, which led to intrahepatic cholestasis of pregnancy, low phospholipid associated cholelithiasis, drug induced liver injury or even progressive familial intrahepatic cholestasis type 3. Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens