Title : NLRP3 inflammasome pathway is involved in olfactory bulb pathological alteration induced by MPTP.

Pub. Date : 2019 Aug

PMID : 30728466






1 Functional Relationships(s)
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1 Furthermore, the olfactory bulbs in MPTP/P-treated mice showed significantly increased levels of interleukin-1beta (IL-1beta), caspase-1, glial fibrillary acidic protein (GFAP), Toll receptor 4 (TLR4), phosphorylation of p65, as well as activated molecules of NOD-like receptor protein 3 (NLRP3) that were associated with neuroinflammation. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine interleukin 1 beta Mus musculus