Title : Romidepsin suppresses monosodium urate crystal-induced cytokine production through upregulation of suppressor of cytokine signaling 1 expression.

Pub. Date : 2019 Feb 6

PMID : 30728075






1 Functional Relationships(s)
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1 METHODS: Peripheral blood mononuclear cells (PBMCs) were cultured with a combination of monosodium urate crystals (MSU) and palmitic acid (C16.0) in order to activate the NLRP3 inflammasome and induce IL-1beta production. Uric Acid NLR family pyrin domain containing 3 Homo sapiens