Title : Pre-treatment with FK506 reduces hepatic ischemia-reperfusion injury in rats.

Pub. Date : 2019 Apr

PMID : 30713033






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, the expression of HO-1 at the level of both transcription and translation increased clearly and the activation of the HIF-1alpha was found in FK506 pre-treated livers. Tacrolimus heme oxygenase 1 Rattus norvegicus
2 CONCLUSION: FK506 pre-treatment could lessen hepatic ischemia-reperfusion injury through up-regulating the expression of HIF-1alpha and HO-1, and inhibiting nuclear translocation of NFAT3 in liver tissues. Tacrolimus heme oxygenase 1 Rattus norvegicus