Pub. Date : 2019 Feb
PMID : 30711936
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AS602801 Sensitizes Ovarian Cancer Stem Cells to Paclitaxel by Down-regulating MDR1. | Paclitaxel | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Knockdown of MDR1 sensitized the cells to paclitaxel, but not to carboplatin or cisplatin. | Paclitaxel | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | CONCLUSION: AS602801 chemosensitized ovarian CSCs to paclitaxel by reducing the expression of MDR1. | Paclitaxel | ATP binding cassette subfamily B member 1 | Homo sapiens |