Pub. Date : 2019 Mar
PMID : 30709701
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Oxyresveratrol protects human lens epithelial cells against hydrogen peroxide-induced oxidative stress and apoptosis by activation of Akt/HO-1 pathway. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |
2 | Oxy increased p-Akt and HO-1 expressions in H2O2-stimulated HLECs. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |
3 | Akt and HO-1 expressions form a regulatory axis and Oxy activated the Akt/HO-1 pathway in H2O2-stimulated HLECs. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |
4 | Akt and HO-1 expressions form a regulatory axis and Oxy activated the Akt/HO-1 pathway in H2O2-stimulated HLECs. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |
5 | Inhibition of the Akt/HO-1 pathway by LY294002 or ZnPP attenuated the effects of Oxy on oxidative stress and apoptosis in H2O2-stimulated HLECs. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |
6 | In conclusion, Oxy protected H2O2-induced oxidative stress and apoptosis through activating the Akt/HO-1 pathway, suggesting the protective effect of Oxy against H2O2-induced cataract. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |
7 | In conclusion, Oxy protected H2O2-induced oxidative stress and apoptosis through activating the Akt/HO-1 pathway, suggesting the protective effect of Oxy against H2O2-induced cataract. | Hydrogen Peroxide | heme oxygenase 1 | Homo sapiens |