Title : Oxyresveratrol protects human lens epithelial cells against hydrogen peroxide-induced oxidative stress and apoptosis by activation of Akt/HO-1 pathway.

Pub. Date : 2019 Mar

PMID : 30709701






7 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Oxyresveratrol protects human lens epithelial cells against hydrogen peroxide-induced oxidative stress and apoptosis by activation of Akt/HO-1 pathway. Hydrogen Peroxide heme oxygenase 1 Homo sapiens
2 Oxy increased p-Akt and HO-1 expressions in H2O2-stimulated HLECs. Hydrogen Peroxide heme oxygenase 1 Homo sapiens
3 Akt and HO-1 expressions form a regulatory axis and Oxy activated the Akt/HO-1 pathway in H2O2-stimulated HLECs. Hydrogen Peroxide heme oxygenase 1 Homo sapiens
4 Akt and HO-1 expressions form a regulatory axis and Oxy activated the Akt/HO-1 pathway in H2O2-stimulated HLECs. Hydrogen Peroxide heme oxygenase 1 Homo sapiens
5 Inhibition of the Akt/HO-1 pathway by LY294002 or ZnPP attenuated the effects of Oxy on oxidative stress and apoptosis in H2O2-stimulated HLECs. Hydrogen Peroxide heme oxygenase 1 Homo sapiens
6 In conclusion, Oxy protected H2O2-induced oxidative stress and apoptosis through activating the Akt/HO-1 pathway, suggesting the protective effect of Oxy against H2O2-induced cataract. Hydrogen Peroxide heme oxygenase 1 Homo sapiens
7 In conclusion, Oxy protected H2O2-induced oxidative stress and apoptosis through activating the Akt/HO-1 pathway, suggesting the protective effect of Oxy against H2O2-induced cataract. Hydrogen Peroxide heme oxygenase 1 Homo sapiens