Title : The influence of alkaloids on oxidative stress and related signaling pathways.

Pub. Date : 2019 Apr

PMID : 30703480






2 Functional Relationships(s)
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1 In some alkaloids, activation of the nuclear factor Nrf2 pathway was documented to be the grounds for inhibition of NADPH-oxidase. Alkaloids NFE2 like bZIP transcription factor 2 Homo sapiens
2 Interestingly, many alkaloids can behave both as anti-oxidants and pro-oxidants depending on conditions and pro-oxidation might be the reason for activation of Nrf2. Alkaloids NFE2 like bZIP transcription factor 2 Homo sapiens