Title : Individual response to mTOR inhibition in delaying replicative senescence of mesenchymal stromal cells.

Pub. Date : 2019

PMID : 30703123






1 Functional Relationships(s)
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1 Despite all rapamycin-treated cells secreted significantly reduced levels of IL6, a major SASP cytokine, and expressed significantly higher levels of the pluripotency marker NANOG, the expression patterns of these markers were not correlated with the rapamycin-mediated increase in lifespan. Sirolimus interleukin 6 Homo sapiens