Pub. Date : 2019 Apr 5
PMID : 30689999
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nimesulide is a relatively selective cyclooxygenase (COX)-2 inhibitor, non-steroidal anti-inflammatory drug; it has been discovered in 1971 and firstly commercialized in Italy in 1985. | nimesulide | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | There is much evidence that the pharmacological profile of nimesulide is peculiar and not shared with the other COX-2 selective inhibitors, suggesting that other molecular mechanisms besides inhibition of COX-2 derived prostaglandins are involved. | nimesulide | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |