Pub. Date : 2019 Feb 28
PMID : 30689946
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the present work, structure optimizations guided by a binding model led to the identification of the lead compound 2-hydroxy-4-((4-(naphthalen-2-yl)thiazol-2-yl)amino)benzoic acid (27), showing a submicromolar potency against purified CK2alpha (IC50 = 0.6 muM). | 2-hydroxy-4-((4-(naphthalen-2-yl)thiazol-2-yl)amino)benzoic acid | casein kinase 2 alpha 2 | Homo sapiens |