Title : A Novel Naphthoquinone-Coumarin Hybrid That Inhibits BCR-ABL1-STAT5 Oncogenic Pathway and Reduces Survival in Imatinib-Resistant Chronic Myelogenous Leukemia Cells.

Pub. Date : 2018

PMID : 30687103






1 Functional Relationships(s)
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1 Notably, NPQ-C6 maintained its activity on BCR-ABL1/STAT5/c-MYC/PIM-1 oncogenic pathway in imatinib-resistant cells. Imatinib Mesylate MYC proto-oncogene, bHLH transcription factor Homo sapiens