Pub. Date : 2019 Jul
PMID : 30686776
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Expression of mito-HIF-1alpha was sufficient to attenuate apoptosis induced by exposure to hypoxia or H2O2-induced oxidative stress. | Hydrogen Peroxide | hypoxia inducible factor 1, alpha subunit | Mus musculus |
| 2 | Moreover, mito-HIF-1alpha expression reduced the production of reactive oxygen species, the collapse of mitochondrial membrane potential, and the expression of mitochondrial DNA-encoded mRNA in response to hypoxia or H2O2 treatment independently of nuclear pathways. | Hydrogen Peroxide | hypoxia inducible factor 1, alpha subunit | Mus musculus |