Title : Heme detoxification by heme oxygenase-1 reinstates proliferative and immune balances upon genotoxic tissue injury.

Pub. Date : 2019 Jan 25

PMID : 30683864






1 Functional Relationships(s)
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1 Collectively, our data indicate that HO-1, by detoxifying heme, blocks p16INK4a expression in macrophages, preventing DNA damage and cellular senescence. Heme heme oxygenase 1 Homo sapiens