Title : Prophylactic potential of memantine against soman poisoning in rats.

Pub. Date : 2019 Mar 15

PMID : 30682440






2 Functional Relationships(s)
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1 Pretreatment with memantine assured higher AChE activity in brain and diaphragm than in unpretreated rats (46% vs 28% and 68% vs. 38%, respectively). Memantine acetylcholinesterase Rattus norvegicus
2 Mechanism of the antidotal effect of memantine against soman poisoning appears to be a combination of AChE-protecting and NMDA receptor-blocking action. Memantine acetylcholinesterase Rattus norvegicus