Title : Long-term efficacy of opicapone in fluctuating Parkinson's disease patients: a pooled analysis of data from two phase 3 clinical trials and their open-label extensions.

Pub. Date : 2019 Jul

PMID : 30681754






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1 BACKGROUND AND PURPOSE: The aim was to evaluate the efficacy of the catechol-O-methyltransferase inhibitor opicapone (25 and 50 mg) as adjunct therapy to levodopa in a pooled population of Parkinson"s disease patients who participated in the pivotal double-blind trials of opicapone and their 1-year open-label extensions. opicapone catechol-O-methyltransferase Homo sapiens