Title : Inhibition of Heme Oxygenase-1 Activity Enhances Wilms Tumor-1-Specific T-Cell Responses in Cancer Immunotherapy.

Pub. Date : 2019 Jan 23

PMID : 30678050






6 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Tin mesoporphyrin (SnMP) is known to inhibit heme oxygenase-1 (HO-1), which has been shown to boost the activation and proliferation of human virus-specific T cells. tin mesoporphyrin heme oxygenase 1 Homo sapiens
2 Tin mesoporphyrin (SnMP) is known to inhibit heme oxygenase-1 (HO-1), which has been shown to boost the activation and proliferation of human virus-specific T cells. tin mesoporphyrin heme oxygenase 1 Homo sapiens
3 Tin mesoporphyrin (SnMP) is known to inhibit heme oxygenase-1 (HO-1), which has been shown to boost the activation and proliferation of human virus-specific T cells. tin mesoporphyrin heme oxygenase 1 Homo sapiens
4 Tin mesoporphyrin (SnMP) is known to inhibit heme oxygenase-1 (HO-1), which has been shown to boost the activation and proliferation of human virus-specific T cells. tin mesoporphyrin heme oxygenase 1 Homo sapiens
5 HO-1 inhibition with SnMP increased WT1-specific T-cell frequencies in 13 (26%) of 50 healthy donors. tin mesoporphyrin heme oxygenase 1 Homo sapiens
6 In conclusion, pharmacological inhibition of HO-1 activity with SnMP results in more efficient generation of functionally active WT1-specific T cells. tin mesoporphyrin heme oxygenase 1 Homo sapiens