Pub. Date : 2019 Mar
PMID : 30664207
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | beta-elemene inhibits oxygen-induced retinal neovascularization via promoting miR-27a and reducing VEGF expression. | beta-elemene | microRNA 27a | Mus musculus |
2 | In addition, beta-elemene treatment upregulate miR-27a expression in vivo and in vitro. | beta-elemene | microRNA 27a | Mus musculus |
3 | When miR-27a expression was depleted by miR-27a inhibitor, the protective effect of beta-elemene on RNV was eliminated. | beta-elemene | microRNA 27a | Mus musculus |
4 | When miR-27a expression was depleted by miR-27a inhibitor, the protective effect of beta-elemene on RNV was eliminated. | beta-elemene | microRNA 27a | Mus musculus |
5 | The present study demonstrated that beta-elemene reduced RNV in mouse OIR models via miR-27a upregulation, leading to reduced VEGF expression. | beta-elemene | microRNA 27a | Mus musculus |