Title : Regulation of the Intracellular ROS Level Is Critical for the Antiproliferative Effect of Quercetin in the Hepatocellular Carcinoma Cell Line HepG2.

Pub. Date : 2019

PMID : 30661409






2 Functional Relationships(s)
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1 Quercetin, an antioxidant flavonoid, has been known that it can induce the cell cycle arrest and apoptosis of hepatocellular carcinoma (HCC) cells by the stabilization or induction of p53. Quercetin tumor protein p53 Homo sapiens
2 This study demonstrates that the antiproliferative effect of quercetin on HCC cells can be mediated by reducing intracellular ROS, which is independent of p53 expression. Quercetin tumor protein p53 Homo sapiens