Pub. Date : 2019 Apr 15
PMID : 30658148
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Polysaccharides from chayote enhance lipid efflux and regulate NLRP3 inflammasome priming in macrophage-like THP-1 cells exposed to cholesterol crystals. | Cholesterol | NLR family pyrin domain containing 3 | Homo sapiens |
2 | Although macrophages are crucial for lipid clearance, the excessive uptake of cholesterol crystals (CC) by these cells induce NLRP3 inflammasome and foam cell formation. | Cholesterol | NLR family pyrin domain containing 3 | Homo sapiens |