Pub. Date : 2019 Jan - Feb
PMID : 30641691
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Comparative study to evaluate the effect of l-carnitine plus glimepiride versus glimepiride alone on insulin resistance in type 2 diabetic patients. | Carnitine | insulin | Homo sapiens |
2 | RESULTS: The obtained data suggested that adding l-carnitine to glimepiride has a significantly beneficial effect on FBG, PPBG, HbA1c, fasting insulin, HOMA-IR index, IRAPe, TNF-alpha, visfatin and lipid panel parameters but doesn"t have effect on BMI and blood pressure. | Carnitine | insulin | Homo sapiens |
3 | CONCLUSION: The co-administration of l-carnitine with glimepiride represents a new therapeutic strategy for better controlling diabetic patients as it resulted in more beneficial effects on direct and indirect biomarkers of insulin resistance than glimepiride alone. | Carnitine | insulin | Homo sapiens |