Title : Rg3 inhibits gemcitabine-induced lung cancer cell invasiveness through ROS-dependent, NF-κB- and HIF-1α-mediated downregulation of PTX3.

Pub. Date : 2019 Jul

PMID : 30628067






2 Functional Relationships(s)
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1 Furthermore, we tested the hypothesis; Rg3 abrogates GEM-induced production of ROS-mediated activation of Akt and extracellular signal-regulated kinase (ERK) pathways and inhibits nuclear piling-up of nuclear factor kappa B (NF-kappaB) and HIF-1alpha. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens
2 Furthermore, we tested the hypothesis; Rg3 abrogates GEM-induced production of ROS-mediated activation of Akt and extracellular signal-regulated kinase (ERK) pathways and inhibits nuclear piling-up of nuclear factor kappa B (NF-kappaB) and HIF-1alpha. Reactive Oxygen Species mitogen-activated protein kinase 1 Homo sapiens