Pub. Date : 2019 Jan 8
PMID : 30626059
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This study aimed to examine whether BPA exposure is associated with the hydroxymethylation level of the sperm ACHE gene. | bisphenol A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Sperm ACHE hydroxymethylation level was higher in the BPA exposure group (p = 0.041) compared to the control group. | bisphenol A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 3 | When subjects were categorized according to tertiles of detected BPA level, higher ACHE hydroxymethylation levels were observed for the lowest, middle, and top tertiles compared to those with BPA below the limit of detection (LOD). | bisphenol A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 4 | In a linear regression analysis adjusted for confounders, a positive linear association between urine BPA concentration and 5-hydroxymethylcytosine (5hmC) rate of the sperm ACHE gene was observed, although the association did not reach statistical significance in all categories after being stratified by the BPA tertile. | bisphenol A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 5 | In a linear regression analysis adjusted for confounders, a positive linear association between urine BPA concentration and 5-hydroxymethylcytosine (5hmC) rate of the sperm ACHE gene was observed, although the association did not reach statistical significance in all categories after being stratified by the BPA tertile. | bisphenol A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 6 | In conclusion, 5hmC of the sperm ACHE gene was positively associated with BPA exposure, which may provide supportive evidence for BPA"s effects on male fertility or other health endpoints. | bisphenol A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 7 | In conclusion, 5hmC of the sperm ACHE gene was positively associated with BPA exposure, which may provide supportive evidence for BPA"s effects on male fertility or other health endpoints. | bisphenol A | acetylcholinesterase (Cartwright blood group) | Homo sapiens |