Pub. Date : 2019 Apr 1
PMID : 30615965
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In this work, binding of anions to the FAD binding pocket of human NAD(P)H:quinone oxidoreductase 1 (NQO1), a flavoprotein associated with cancer due to a common polymorphism causing a P187S amino acid substitution, was investigated. | Flavin-Adenine Dinucleotide | NAD(P)H quinone dehydrogenase 1 | Homo sapiens |
| 2 | In this work, binding of anions to the FAD binding pocket of human NAD(P)H:quinone oxidoreductase 1 (NQO1), a flavoprotein associated with cancer due to a common polymorphism causing a P187S amino acid substitution, was investigated. | Flavin-Adenine Dinucleotide | NAD(P)H quinone dehydrogenase 1 | Homo sapiens |
| 3 | Herein, binding and protein stability analyses were carried out to show that anion binding to the apo-state of NQO1 P187S inhibits FAD binding with increasing strength following the chaotropic behavior of anions. | Flavin-Adenine Dinucleotide | NAD(P)H quinone dehydrogenase 1 | Homo sapiens |