Title : Interferon-γ regulates cell malignant growth via the c-Abl/HDAC2 signaling pathway in mammary epithelial cells.

Pub. Date : 2019 Jan.

PMID : 30614229






2 Functional Relationships(s)
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1 The HDAC2 inhibitor, valproate (VPA) and the c-Abl inhibitor, imatinib, lowered the expression level of cyclin D1/CDK4, and increased the expression level of p21, leading to an inhibitory effect on IFN-gamma-induced malignant cell growth. Valproic Acid cyclin dependent kinase inhibitor 1A Bos taurus
2 The HDAC2 inhibitor, valproate (VPA) and the c-Abl inhibitor, imatinib, lowered the expression level of cyclin D1/CDK4, and increased the expression level of p21, leading to an inhibitory effect on IFN-gamma-induced malignant cell growth. Valproic Acid cyclin dependent kinase inhibitor 1A Bos taurus