Pub. Date : 2019 Apr
PMID : 30604098
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | All insulin superfamily members contain three absolutely conserved disulfide linkages and a nonchiral Gly residue immediately following the first B-chain cysteine. | Glycine | insulin | Homo sapiens |
2 | The functionality of this conserved Gly residue in the insulin family has been studied by replacing it with natural L-amino acids or the corresponding unnatural D-amino acids. | Glycine | insulin | Homo sapiens |
3 | The present study revealed functionality of the conserved B-chain Gly residue for a relaxin family peptide for the first time, providing an overview of its contribution to foldability and activity of the insulin superfamily. | Glycine | insulin | Homo sapiens |