Title : Curcumin and quercetin synergistically inhibit cancer cell proliferation in multiple cancer cells and modulate Wnt/β-catenin signaling and apoptotic pathways in A375 cells.

Pub. Date : 2019 Jan

PMID : 30599890






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1 Further investigation of the mechanism of action of curcumin and quercetin in melanoma cells, A375, suggested that inhibition of cell proliferation occurred through down-regulation of Wnt/beta-catenin signaling pathway proteins, DVL2, beta-catenin, cyclin D1, Cox2, and Axin2. Curcumin mitochondrially encoded cytochrome c oxidase II Homo sapiens