Title : Functional characterization of novel ALOX15 orthologs representing key steps in mammalian evolution supports the Evolutionary Hypothesis of reaction specificity.

Pub. Date : 2019 Mar

PMID : 30599203






1 Functional Relationships(s)
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1 Most mammalian genomes involve six or seven functional ALOX genes and among the corresponding ALOX-isoforms the ALOX15 orthologs are somewhat unique since they exhibit variable reaction specificity using arachidonic acid as substrate. Arachidonic Acid arachidonate 15-lipoxygenase Homo sapiens