Title : Niacin fine-tunes energy homeostasis through canonical GPR109A signaling.

Pub. Date : 2019 Apr

PMID : 30596513






4 Functional Relationships(s)
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1 Niacin fine-tunes energy homeostasis through canonical GPR109A signaling. Niacin hydroxycarboxylic acid receptor 2 Mus musculus
2 Additionally, we demonstrated that niacin treatment triggered brown adipose tissue and/or white adipose tissue thermogenic activity via activation of GPR109A. Niacin hydroxycarboxylic acid receptor 2 Mus musculus
3 Taken together, our findings demonstrate that acting on GPR109A, niacin shows the potential to maintain energy homeostasis through multipathways, representing a potential approach to the treatment of obesity, diabetes and cardiovascular disease.-Ye, L., Cao, Z., Lai, X., Wang, W., Guo, Z., Yan, L., Wang, Y., Shi, Y., Zhou, N. Niacin fine-tunes energy homeostasis through canonical GPR109A signaling. Niacin hydroxycarboxylic acid receptor 2 Mus musculus
4 Taken together, our findings demonstrate that acting on GPR109A, niacin shows the potential to maintain energy homeostasis through multipathways, representing a potential approach to the treatment of obesity, diabetes and cardiovascular disease.-Ye, L., Cao, Z., Lai, X., Wang, W., Guo, Z., Yan, L., Wang, Y., Shi, Y., Zhou, N. Niacin fine-tunes energy homeostasis through canonical GPR109A signaling. Niacin hydroxycarboxylic acid receptor 2 Mus musculus