Title : Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events.

Pub. Date : 2019 Mar 5

PMID : 30595457






1 Functional Relationships(s)
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1 We also establish that CtHsp104 antagonizes several toxic protein-misfolding events in vivo where S. cerevisiae Hsp104 is ineffective, including rescue of TDP-43, polyglutamine, and alpha-synuclein toxicity. polyglutamine chaperone ATPase HSP104 Saccharomyces cerevisiae S288C